ctxa hip software version 4.1 Search Results


ctxa hip module  (Mindways Software)
86
Mindways Software ctxa hip module
Automatic selection of regions of interest (ROIs) <t>for</t> <t>QCT</t> analysis. Axial CT slice processed with the <t>CTXA</t> Hip module (QCT Pro, Mindways). The green boxes indicate the automated placement of the hip ROI and the calibration phantom, which are used to extract bone mineral density values for osteoporosis assessment.
Ctxa Hip Module, supplied by Mindways Software, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctxa+hip+module+pro+qct/pmc12578436-58-6-11
Average 86 stars, based on 1 article reviews
ctxa hip module - by Bioz Stars, 2026-10
86/100 stars
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matrix assisted laser desorption/ionisation - time of flight mass spectrometry  (Kirstein GmbH)
90
Kirstein GmbH matrix assisted laser desorption/ionisation - time of flight mass spectrometry
Automatic selection of regions of interest (ROIs) <t>for</t> <t>QCT</t> analysis. Axial CT slice processed with the <t>CTXA</t> Hip module (QCT Pro, Mindways). The green boxes indicate the automated placement of the hip ROI and the calibration phantom, which are used to extract bone mineral density values for osteoporosis assessment.
Matrix Assisted Laser Desorption/Ionisation Time Of Flight Mass Spectrometry, supplied by Kirstein GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/matrix+assisted+laser+desorption+ionisation+++time+of+flight+mass+spectrometry/pm35129968__es1c05405_si_001-517-55-66
Average 90 stars, based on 1 article reviews
matrix assisted laser desorption/ionisation - time of flight mass spectrometry - by Bioz Stars, 2026-10
90/100 stars
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primers ctxa1 ctxa2  (Sigma-Genosys)
90
Sigma-Genosys primers ctxa1 ctxa2
Automatic selection of regions of interest (ROIs) <t>for</t> <t>QCT</t> analysis. Axial CT slice processed with the <t>CTXA</t> Hip module (QCT Pro, Mindways). The green boxes indicate the automated placement of the hip ROI and the calibration phantom, which are used to extract bone mineral density values for osteoporosis assessment.
Primers Ctxa1 Ctxa2, supplied by Sigma-Genosys, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/primers+ctxa1+ctxa2/pm15357715-90-49-56
Average 90 stars, based on 1 article reviews
primers ctxa1 ctxa2 - by Bioz Stars, 2026-10
90/100 stars
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ctx4a  (Japan Food Research Laboratories)
90
Japan Food Research Laboratories ctx4a
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ctx4a, supplied by Japan Food Research Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctx4a/pmc11053878-55-19-24
Average 90 stars, based on 1 article reviews
ctx4a - by Bioz Stars, 2026-10
90/100 stars
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ctxa probe  (Kaneka Corp)
86
Kaneka Corp ctxa probe
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ctxa Probe, supplied by Kaneka Corp, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctxa+probe/10__9734_slash_mrji_slash_2021_slash_v31i630322-100-9-11
Average 86 stars, based on 1 article reviews
ctxa probe - by Bioz Stars, 2026-10
86/100 stars
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ssdna− ctxa−azide  (Bio-Synthesis Inc)
90
Bio-Synthesis Inc ssdna− ctxa−azide
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ssdna− Ctxa−Azide, supplied by Bio-Synthesis Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ssdna++ctxa+azide/pm34128638-195-17-19
Average 90 stars, based on 1 article reviews
ssdna− ctxa−azide - by Bioz Stars, 2026-10
90/100 stars
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ctxa technique  (Mindways Software)
86
Mindways Software ctxa technique
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ctxa Technique, supplied by Mindways Software, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctxa+technique/pmc12465813-121-24-28
Average 86 stars, based on 1 article reviews
ctxa technique - by Bioz Stars, 2026-10
86/100 stars
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ctxb  (ImmunoGen Inc)
90
ImmunoGen Inc ctxb
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ctxb, supplied by ImmunoGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctxb/us07422752-9-20-5
Average 90 stars, based on 1 article reviews
ctxb - by Bioz Stars, 2026-10
90/100 stars
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metamorph software  (MetaMorph Inc)
90
MetaMorph Inc metamorph software
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Metamorph Software, supplied by MetaMorph Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/metamorph+software/pmc06393602-275-22-46
Average 90 stars, based on 1 article reviews
metamorph software - by Bioz Stars, 2026-10
90/100 stars
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ctx3  (Bachem)
90
Bachem ctx3
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Ctx3, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/ctx+3/10__1074_slash_jbc__m110__185405-47-0-3
Average 90 stars, based on 1 article reviews
ctx3 - by Bioz Stars, 2026-10
90/100 stars
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oxidized ctxs  (SATAKE)
90
SATAKE oxidized ctxs
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Oxidized Ctxs, supplied by SATAKE, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/oxidized+ctxs/pm39567072-102-13-39
Average 90 stars, based on 1 article reviews
oxidized ctxs - by Bioz Stars, 2026-10
90/100 stars
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celltiter-glo (ctg) assay  (Promega)
90
Promega celltiter-glo (ctg) assay
LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), <t>CTX4A</t> (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.
Celltiter Glo (Ctg) Assay, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ctxa+hip+software+version+4%2E1/celltiter+glo+luminescent+cell+viability+assay/pmc10987804__BLOODA_ADV___2023___010435___mmc1-9-11-14
Average 90 stars, based on 1 article reviews
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90/100 stars
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Image Search Results


Automatic selection of regions of interest (ROIs) for QCT analysis. Axial CT slice processed with the CTXA Hip module (QCT Pro, Mindways). The green boxes indicate the automated placement of the hip ROI and the calibration phantom, which are used to extract bone mineral density values for osteoporosis assessment.

Journal: SICOT-J

Article Title: Prevalence of low bone mineral density in robotic-assisted TKA candidates: insights from quantitative CT analysis

doi: 10.1051/sicotj/2025048

Figure Lengend Snippet: Automatic selection of regions of interest (ROIs) for QCT analysis. Axial CT slice processed with the CTXA Hip module (QCT Pro, Mindways). The green boxes indicate the automated placement of the hip ROI and the calibration phantom, which are used to extract bone mineral density values for osteoporosis assessment.

Article Snippet: Axial CT slice processed with the CTXA Hip module (QCT Pro, Mindways).

Techniques: Selection

LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), CTX4A (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.

Journal: Toxins

Article Title: Detection of Extremely Low Level Ciguatoxins through Monitoring of Lithium Adduct Ions by Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

doi: 10.3390/toxins16040170

Figure Lengend Snippet: LC-MS/MS (MRM mode) chromatograms of the NIHS-CTX-Mix comprised of CTX1B (1.00 ng/mL), 2.3-dihydroxyCTX3C (2.80 ng/mL), 52- epi -54-deoxyCTX1B (1.45 ng/mL), 51-hydroxy-CTX3C (2.70 ng/mL), 54-deoxyCTX1B (1.15 ng/mL), 49- epi CTX3C (1.20 ng/mL), CTX3C (1.05 ng/mL), CTX4A (1.50 ng/mL), and CTX4B (1.10 ng/mL). Analyses were carried out with acetonitrile-based mobile phases containing ( A ) Na + and ( B ) Li + and MRM transitions were set as [M+Na] + > [M+Na] + and [M+Li] + > [M+Li] + , respectively. The LC-MS/MS conditions are shown in . ( A ) [M+Na] + > [M+Na] + : CTX1B m / z 1133.60 > 1133.60, 2.3-dihydroxyCTX3C m / z 1079.60 > 1079.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1117.60 > 1117.60, 51-hydroxyCTX3C m / z 1061.60 > 1061.60, 49- epi CTX-3C and CTX-3C m / z 1045.60 > 1045.60, CTX4A and CTX4B m / z 1083.60 > 1083.60. ( B ) [M+Li] + > [M+Li] + : CTX1B m / z 1117.60 > 1117.60, 2.3-dihydroxyCTX3C m / z 1063.60 > 1063.60, 52- epi -54-deoxyCTX1B and 54-deoxyCTX1B m / z 1101.60 > 1101.60, 51-hydroxyCTX3C m / z 1045.60 > 1045.60, 49- epi CTX3C, and CTX3C m / z 1029.60 > 1029.60, CTX4A and CTX4B m / z 1067.60 > 1067.60.

Article Snippet: The CTX mix solution (JFRL-CTX-Mix) was prepared from five CTX reference materials: CTX1B, 52- epi -54-deoxyCTX1B, 51-hydroxyCTX3C, CTX3C, and CTX4A (JFRL-CTX-RMs), supplied by JFRL (Japan Food Research Laboratories, Tokyo, Japan).

Techniques: Liquid Chromatography with Mass Spectroscopy

LC-MS/MS chromatograms at the lowest calibration point of CTX analogs in the JFRL-CTX-Mix. ( a ) CTX1B: 0.0022 ng/mL, ( b ) 52- epi -54-deoxyCTX1B: 0.0060 ng/mL, ( c ) 51-hydroxyCTX3C: 0.0055 ng/mL, ( d ) CTX3C: 0.0050 ng/mL, and ( e ) CTX4A: 0.0055 ng/mL.

Journal: Toxins

Article Title: Detection of Extremely Low Level Ciguatoxins through Monitoring of Lithium Adduct Ions by Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

doi: 10.3390/toxins16040170

Figure Lengend Snippet: LC-MS/MS chromatograms at the lowest calibration point of CTX analogs in the JFRL-CTX-Mix. ( a ) CTX1B: 0.0022 ng/mL, ( b ) 52- epi -54-deoxyCTX1B: 0.0060 ng/mL, ( c ) 51-hydroxyCTX3C: 0.0055 ng/mL, ( d ) CTX3C: 0.0050 ng/mL, and ( e ) CTX4A: 0.0055 ng/mL.

Article Snippet: The CTX mix solution (JFRL-CTX-Mix) was prepared from five CTX reference materials: CTX1B, 52- epi -54-deoxyCTX1B, 51-hydroxyCTX3C, CTX3C, and CTX4A (JFRL-CTX-RMs), supplied by JFRL (Japan Food Research Laboratories, Tokyo, Japan).

Techniques: Liquid Chromatography with Mass Spectroscopy

The calibration curves of the CTX analogs. ( a ) CTX1B (0.0022–0.110 ng/mL), ( b ) 52- epi -54-deoxyCTX1B (0.0060–0.120 ng/mL), ( c ) 51-hydroxyCTX3C (0.0055–0.110 ng/mL), ( d ) CTX3C (0.0050–0.100 ng/mL), ( e ) CTX4A (0.0055–0.110 ng/mL).

Journal: Toxins

Article Title: Detection of Extremely Low Level Ciguatoxins through Monitoring of Lithium Adduct Ions by Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

doi: 10.3390/toxins16040170

Figure Lengend Snippet: The calibration curves of the CTX analogs. ( a ) CTX1B (0.0022–0.110 ng/mL), ( b ) 52- epi -54-deoxyCTX1B (0.0060–0.120 ng/mL), ( c ) 51-hydroxyCTX3C (0.0055–0.110 ng/mL), ( d ) CTX3C (0.0050–0.100 ng/mL), ( e ) CTX4A (0.0055–0.110 ng/mL).

Article Snippet: The CTX mix solution (JFRL-CTX-Mix) was prepared from five CTX reference materials: CTX1B, 52- epi -54-deoxyCTX1B, 51-hydroxyCTX3C, CTX3C, and CTX4A (JFRL-CTX-RMs), supplied by JFRL (Japan Food Research Laboratories, Tokyo, Japan).

Techniques:

Evaluation results for the lowest point on the calibration curve (LOQ).

Journal: Toxins

Article Title: Detection of Extremely Low Level Ciguatoxins through Monitoring of Lithium Adduct Ions by Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

doi: 10.3390/toxins16040170

Figure Lengend Snippet: Evaluation results for the lowest point on the calibration curve (LOQ).

Article Snippet: The CTX mix solution (JFRL-CTX-Mix) was prepared from five CTX reference materials: CTX1B, 52- epi -54-deoxyCTX1B, 51-hydroxyCTX3C, CTX3C, and CTX4A (JFRL-CTX-RMs), supplied by JFRL (Japan Food Research Laboratories, Tokyo, Japan).

Techniques: